The Indian Journal of Nutrition and Dietetics

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Iodine Nutritional Status among Pregnant Women of Murshidabad District in West Bengal


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1 Department of Physiology, Berhampore Girls' College, P.O. Berhampore Dist, Murshidabad, West Bengal - 742 101, India
     

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Iodine Deficiency Disorders (IDD) is a significant public health problem in the world including India. Although the number of countries with iodine deficiency decreased, still in several studies conducted around the world the pregnant women have been found to be particularly vulnerable to IDD. Totally 315 pregnant women (aged between 18-45 yrs) were clinically examined for goiter from three sub divisions of Murshidabad district. The overall goiter prevalence was found to be 18.7%. Most of the goiter was palpable (grade 1) however, visible goiter also existed. To evaluate the occurrence of associated iodine deficiency disorders (IDD) every pregnant woman was examined or enquired individually. In the studied population, most prevalent abnormalities were feeble mindedness (38.4%) followed by deaf mutism (10.4%), squint (1.9%), miscarriage (8.3%) and still birth (2.5%). Urinary iodine and thiocyanate concentrations were measured for all subjects and the mean and median Urinary Iodine (UI) were found to be 12.6 ± 9.3 μg/dl and 11.1 μg/dl respectively. The mean and median thiocyanate excretion levels were 0.614 ± 0.23 mg/dl and 0.545 mg/dl respectively. The overall clinical observations suggest that the pregnant women of the studied region are affected by goiter or they are iodine deficient but biochemically they have no iodine deficiency as evidenced by their urinary iodine excretion pattern. They consume foods containing thiocyanate precursors as evidenced by urinary thiocyanate excretion pattern. Thus in spite of the consumption of adequate iodine, existing goiter prevalence may be due to the consumption of dietary goitrogens/antithyroid substances that possibly come through food and water.

Keywords

Iodine, Iodine Deficiency Disorders (IDD), Pregnant Women, Urinary Iodine, Urinary Thiocyanate.
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  • Hetzel, B.S. Iodine deficiency disorders (IDD) and their eradication. Lancet, 1983, 2, 1126-1129.

  • Hetzel, B.S., Pandav, C.S. SOS for a Billion. Oxford University Press. Delhi 1994: 1-26.

  • Tripathy, S., Halder, G.C. and Debnath, A. Age, sex, religion and caste specific goitre prevalence among school children in Berhampore sadar sub-division of Murshidabad district, West Bengal. Al. Ameen. J. Med. Sci., 2013, 6, 183-188.

  • Tripathy, S. Prevalence of goitre among muslim school children in Domkol sub-division of Murshidabad district, West Bengal. Ind. J. Nutr. Dietet., 2013, 50, 162-167.

  • Karmarkar, M.G., Pandav, C.S. and Krishnamachari, K.A.V.R. Principle and procedure for iodine estimation. A laboratory manual, New Delhi, Indian Council of Medical Research, 1986.

  • Aldridge, W.N. The estimation of micro quantities of cyanide and thiocyanate. Analyst, 1945, 70, 474-475.

  • Michajlovskij, N. and Langer, P. Studien uber Benziehungen Zwischen Rhodanbildung und Kropfbildender Eigenschaft Von Nahrungsmitteln. In: Gehalt einiger Nahrungs Mittel an praformierten Rhodanid. Z. Physiol Chem., 1958, 312, 26-30.

  • WHO/UNICEF/ICCIDD. Indicators for tracking progress in IDD elimination. IDD Newsletter 1994, 10, 37-41.

  • Levin, H.M. Economic dimensions of Iodine Deficiency Disorders. In: Hetzel, B.S., Dunn, J.T. and Stanbury, J.B. (Eds). The prevention and control of iodine deficiency disorders. 1987, 195-208. Elsevier, Amsterdam.

  • WHO, UNICEF, ICCIDD. Assessment of the Iodine Deficiency Disorders and monitoring their eliminations. Geneva: WHO Publ, WHO/NHD/01.1.1-107, 2001.

  • Dunn, J.T., Vander and Haar, F. Detection of iodine deficiency. In: A practical guide to the correction of Iodine Deficiency. Technical Manual No.3. The Netherlands : ICCIDD/UNICEF/WHO Publication; 1990; 13-20.

  • Queriodo, O., Delange, F., Dunn, T., Fierro-Benitez, R. and Ibbertson, H.K et al. Definition of endemic goitre and cretinism, classification of goitre size and severity of endemias and survey techniques. In: J.T. Dunn, G.A and Medeiros-Neto, editors. Endemic goitre and cretinism: Continuing threats to world health (Pan American Health Organisation, Washington DC, USA, Sci Publ), 1974, 292, 267.

  • Delange, F., Thilly, C., Bourdoux, P., Hennart, P., Courtois, P., Ermans, A.M. Influence of dietary goitrogens during pregnancy in humans on thyroid function of the newborn. In: Delange, F., Iteke, F.B., Ermans, A.M., editors. Nutritional factors involved in the goitrogenic action of cassava. IDRC-184e, Int Dev Res, Cent, Ottawa, 1982, 40-50.

  • Kochupillai, N. Neonatal hypothyroidism in India. Mount Sinai Med., 1992, 59, 111-115.

  • Chandra, A.K., Ray, I. Evaluation of the effectiveness of salt iodization status in Tripura, Northeast India. Ind. J. Med. Res., 2002, 115, 22-27.

  • Chandra, A.K., Mukhopadhyay, S., Lahari, D. and Tripathy, S. Goitrogenic content of cyanogenic plant foods of Indian origin and their anti-thyroidal activity in vitro. Ind. J. Med. Res., 2004, 119, 180-185.

  • Marwaha, R.K., Tandon, N., Gupta, N., Karak, A.K, Verma, K. and Kochupillai, N. Residual goitre in the post-iodization phase: iodine status, thiocyanate exposure and autoimmunity.

  • Clin. Endocrinol., 2003, 59, 672-681.


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  • Iodine Nutritional Status among Pregnant Women of Murshidabad District in West Bengal

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Authors

Smritiratan Tripathy
Department of Physiology, Berhampore Girls' College, P.O. Berhampore Dist, Murshidabad, West Bengal - 742 101, India

Abstract


Iodine Deficiency Disorders (IDD) is a significant public health problem in the world including India. Although the number of countries with iodine deficiency decreased, still in several studies conducted around the world the pregnant women have been found to be particularly vulnerable to IDD. Totally 315 pregnant women (aged between 18-45 yrs) were clinically examined for goiter from three sub divisions of Murshidabad district. The overall goiter prevalence was found to be 18.7%. Most of the goiter was palpable (grade 1) however, visible goiter also existed. To evaluate the occurrence of associated iodine deficiency disorders (IDD) every pregnant woman was examined or enquired individually. In the studied population, most prevalent abnormalities were feeble mindedness (38.4%) followed by deaf mutism (10.4%), squint (1.9%), miscarriage (8.3%) and still birth (2.5%). Urinary iodine and thiocyanate concentrations were measured for all subjects and the mean and median Urinary Iodine (UI) were found to be 12.6 ± 9.3 μg/dl and 11.1 μg/dl respectively. The mean and median thiocyanate excretion levels were 0.614 ± 0.23 mg/dl and 0.545 mg/dl respectively. The overall clinical observations suggest that the pregnant women of the studied region are affected by goiter or they are iodine deficient but biochemically they have no iodine deficiency as evidenced by their urinary iodine excretion pattern. They consume foods containing thiocyanate precursors as evidenced by urinary thiocyanate excretion pattern. Thus in spite of the consumption of adequate iodine, existing goiter prevalence may be due to the consumption of dietary goitrogens/antithyroid substances that possibly come through food and water.

Keywords


Iodine, Iodine Deficiency Disorders (IDD), Pregnant Women, Urinary Iodine, Urinary Thiocyanate.

References